Induced muscle differentiation in an embryonal carcinoma cell line.
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چکیده
منابع مشابه
Growth and differentiation of an embryonal carcinoma cell line (C145b).
Several cell and tumour lines were isolated from a single-embryo-derived teratocarcinoma and their karyotypes and differentiation in adult hosts recorded. The majority of cells contained normal karyotypes by banding. The cells were injected into blastocysts and although they sometimes colonized the yolk sac, they never colonized the embryo. Thus the possession of a normal karyotype is not a suf...
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The murine embryonal carcinoma cell line P19S1801Al develops into neuronlike cells after treatment with retinoic acid (Edwards and McBurney, 1983). We have analyzed the expression of cell surface carbohydrate antigens and intracellular cytoskeletal antigens in differentiating OlAl cells in order to identify the cell types present in the cultures and to characterize the differentiation process. ...
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P10 is a line of embryonal carcinoma cells with a euploid female karyotype. By making use of variant alleles of X-linked genes and of cytogenetic procedures, we have previously shown that the P10 cells have two genetically active X chromosomes. We show here that P10 cells rapidly differentiate into a cell type resembling extraembryonic endoderm when cultured in the presence of retinoic acid. Th...
متن کاملUltrastructural differentiation of a clonal human embryonal carcinoma cell line in vitro.
A cloned human embryonal carcinoma (EC) cell line 2102Ep derived from a testicular teratocarcinoma was characterized by means of electron microscopy and immunohistochemistry. These EC cells when plated at high cell density grow mostly as undifferentiated cells displayed relatively little pleomorphism. Eighty-five to 90% of these cells contain keratin in the form of peridesmosomal tonofilaments....
متن کاملChanges in c-onc expression during embryonal carcinoma cell differentiation.
Protooncogenes expressed in murine embryonal carcinoma (EC) cells or their differentiated daughter cells include more or less ubiquitously expressed protooncogenes such as c-myc, c-K-ras, and c-abl, as well as c-onc genes with a very restricted expression pattern. Examples of the latter are N-myc, c-mos, and int-2. These c-onc genes are transcriptionally active in EC cells, as well as in germ c...
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ژورنال
عنوان ژورنال: Molecular and Cellular Biology
سال: 1983
ISSN: 0270-7306,1098-5549
DOI: 10.1128/mcb.3.12.2280